File:DE cycle.png

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English: An example of directed evolution with comparison to natural evolution. The inner cycle indicates the 3 stages of the directed evolution cycle with the natural process being mimicked in brackets. The outer circle demonstrates steps a typical experiment. The red symbols indicate functional variants, the pale symbols indicate variants with reduced function.
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Umthombo Thomas, Shafee, (2014). "Evolvability of a viral protease: experimental evolution of catalysis, robustness and specificity". PhD Thesis. University of Cambridge.
Umlobi Thomas Shafee
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