File:PegUricase.png

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English: A comparison of uricase (pdb:1uox) and PEG-uricase (model). PEG-uricase includes 40 polymers of 10kDa PEG. PEGylation improves its solubility at physiological pH, increases serum half-life and reduces immunogenicity without compromising activity. Upper images show the whole tetramer, lower images show an example of one of the lysines that is PEGylated. (PEG-uricase model from reference[1], only 36 PEG polymers included)
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Umthombo Own work
Umlobi Evolution and evolvability

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  1. ↑ (3 January 2008). "PEG-uricase in the management of treatment-resistant gout and hyperuricemia.". Advanced drug delivery reviews 60 (1): 59-68. PMID 17826865.

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depicts i-English

PEGylation i-English

pegloticase i-English

uricase i-English

copyright status i-English

copyrighted i-English

inception i-English

22 uNhlolanja 2015

Umlando womqulu

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Njengamanje23:50, 21 uNhlolanja 2015Isithonjana senguquko eyenziwa nge-23:50, 21 uNhlolanja 20152,192 × 2,136 (1.65 MB)Evolution and evolvabilityUser created page with UploadWizard

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